[小鼠中针对泰泽氏病的胸腺依赖性免疫]
[Thymus dependent immunity against Tyzzer's disease in the mouse].
作者信息
Fujiwara K, Machii K, Nakayama M, Tamura T, Ueda K
出版信息
C R Seances Soc Biol Fil. 1977;171(3):710-4.
PMID:144015
Abstract
Nude (nu/nu) mice fail to resist to challenge infection of Tyzzer's disease after pretreatment with formalin-killed organisms that was effective for protecting heterozygous haired (nu/ł) mice from challenge. Resistance was induced nu/nu mice after the transfer of spleen cells from immunized nu/ł and concomitant formalin vaccine treatment.
摘要
裸（nu/nu）小鼠在用福尔马林灭活的病原体进行预处理后，无法抵抗泰泽氏病的攻击感染，而这种预处理对保护杂合有毛（nu/ł）小鼠免受攻击是有效的。在将免疫过的nu/ł小鼠的脾细胞转移给nu/nu小鼠并同时进行福尔马林疫苗处理后，诱导了nu/nu小鼠的抵抗力。
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