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[被忽视的过敏原]

[Neglected allergens].

作者信息

Glück U

机构信息

Pneumologische Abteilung, Medizinische Universitätsklinik, Bern.

出版信息

Ther Umsch. 1992 Oct;49(10):669-73.

PMID:1440434
Abstract

The atopic symptoms manifest themselves mainly in hay fever or bronchial asthma. In a not inconsiderable number of cases, the question of oral complaints, connected with the intake of certain foodstuffs, is ignored in the medical anamnesis. Here, we are dealing with what is known as food-associated allergy syndrome, which is largely based on a cross reaction between certain types of pollen (birch, alder, hazel and mugwort) and food allergens (drupes, pomes, nuts, vegetables such as celery, carrots and fennel, etc.). Whereas following the intake of fruit the complaints are usually restricted solely to the oral cavity and the throat (aphthas, stomatitis, swelling of the lips and/or tongue, irritation of the hard palate, hoarseness and compulsive clearing of the throat), nuts and celery among others from the family Compositae often cause acute, allergic attacks with sometimes serious general symptoms such as laryngeal oedema, bronchial asthma, urticaria and even anaphylactic shock. In the sensitization against animal allergens, it must not be forgotten that the most powerful immunogens are to be found, for example, in the urine of small rodents (mice and rats). In the manufacture or application of fish food with red gnat larvae, people who are disposed to this will often react with an attack of bronchial asthma.

摘要

特应性症状主要表现为花粉热或支气管哮喘。在相当多的病例中,医学问诊中会忽略与某些食物摄入相关的口腔不适问题。这里,我们所涉及的是所谓的食物相关过敏综合征,它主要基于某些类型的花粉(桦树、桤木、榛树和艾蒿)与食物过敏原(核果、梨果、坚果、蔬菜如芹菜、胡萝卜和茴香等)之间的交叉反应。摄入水果后,不适通常仅局限于口腔和喉咙(口疮、口腔炎、嘴唇和/或舌头肿胀、硬腭刺激、声音嘶哑和强迫性清嗓),而菊科植物中的坚果和芹菜等常常会引发急性过敏反应,有时还伴有严重的全身症状,如喉头水肿、支气管哮喘、荨麻疹甚至过敏性休克。在对动物过敏原的致敏过程中,绝不能忘记,例如在小型啮齿动物(小鼠和大鼠)的尿液中能发现最强的免疫原。在生产或使用含有红色蚋幼虫的鱼食时,易患此病的人常常会引发支气管哮喘发作。

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