KITCHIN A H, KONZETT H, PICKFORD M
Br J Pharmacol Chemother. 1959 Dec;14(4):567-70. doi: 10.1111/j.1476-5381.1959.tb00965.x.
Valyl(3)-oxytocin has similar circulatory effects in man to those of Syntocinon (synthetic oxytocin). On intravenous administration, it caused a rise in limb blood flow and in pulse rate and a fall in blood pressure. It had a direct vasodilator effect on limb blood vessels. Valyl(3)-oxytocin was 1.5 to 2 times more potent than Syntocinon in terms of its circulatory effect in man. The circulatory effects of valyl(3)-oxytocin were less readily antagonized by vasopressin than are those of Syntocinon.
缬氨酰（3）-催产素对人体的循环系统作用与合成缩宫素（合成催产素）相似。静脉注射时，它会使肢体血流量增加、脉搏率上升以及血压下降。它对肢体血管有直接的血管舒张作用。就对人体的循环系统作用而言，缬氨酰（3）-催产素的效力比合成缩宫素强1.5至2倍。与合成缩宫素相比，缬氨酰（3）-催产素的循环系统作用较不易被血管加压素拮抗。
