补体抗原特性的研究。I. 针对固定在致敏绵羊红细胞上的豚鼠补体的凝集抗体的证明。
Studies on the antigenic properties of complement. I. Demonstration of agglutinating antibodies against guinea pig complement fixed on sensitized sheep erythrocytes.
作者信息
KLEIN P G, BURKHOLDER P M
出版信息
J Exp Med. 1960 Jan 1;111(1):93-106. doi: 10.1084/jem.111.1.93.
Abstract
Evidence is presented to show that guinea pig complement fixed on sensitized sheep red cells acts as a specific agglutinogen. Agglutinating antibodies that react with cell-fixed complement can be produced by immunizing rabbits with a complex of stromata-amboceptor-complement or with guinea pig serum globulin. These agglutinins can be removed by precipitation with guinea pig serum. They are, therefore, distinct from immunoconglutinins.
摘要
有证据表明，固定在致敏绵羊红细胞上的豚鼠补体可作为一种特异性凝集原。通过用基质-双受体-补体复合物或豚鼠血清球蛋白免疫兔子，可产生与细胞固定补体发生反应的凝集抗体。这些凝集素可用豚鼠血清沉淀去除。因此，它们与免疫胶固素不同。
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