补体抗原特性的研究。II. 针对固定在致敏绵羊红细胞上的豚鼠补体某些成分的特异性凝集素分析。
Studies on the antigenic properties of complement. II. Analysis of specific agglutinins against certain components of guinea pig complement fixed on sensitized sheep erythrocytes.
作者信息
KLEIN P G, BURKHOLDER P M
出版信息
J Exp Med. 1960 Jan 1;111(1):107-17. doi: 10.1084/jem.111.1.107.
Abstract
Sheep erythrocytes sensitized with amboceptor and persensitized thereafter with guinea pig complement are agglutinated by rabbit anti-guinea pig globulin and by immune sera obtained by injection of rabbits with fixed complement. In this agglutination neither C'1 nor C'2 takes part. Fixed C'4 acts as an agglutinogen. An additional agglutinogen, distinct from C'4, was found on persensitized cells. This additional agglutinogen appears to be distinct from hemolytically active C'3.
摘要
用双价抗体致敏的绵羊红细胞，随后再用豚鼠补体进行再致敏，会被兔抗豚鼠球蛋白以及通过给兔子注射固定补体而获得的免疫血清所凝集。在这种凝集反应中，C'1和C'2均不参与。固定的C'4作为一种凝集原起作用。在再致敏细胞上发现了一种不同于C'4的额外凝集原。这种额外凝集原似乎与具有溶血活性的C'3不同。
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本文引用的文献
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Studies on the antigenic properties of complement. I. Demonstration of agglutinating antibodies against guinea pig complement fixed on sensitized sheep erythrocytes.补体抗原特性的研究。I. 针对固定在致敏绵羊红细胞上的豚鼠补体的凝集抗体的证明。
J Exp Med. 1960 Jan 1;111(1):93-106. doi: 10.1084/jem.111.1.93.
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Studies on immune hemolysis: preparation of a stable and highly reactive complex of sensitized erythrocytes and the first component of complement (EAC'1): inactivation of cell-fixed C'1 by some complement reagents.免疫溶血研究：致敏红细胞与补体第一成分（EAC'1）稳定且高反应性复合物的制备：某些补体试剂对细胞固定C'1的灭活作用
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