实验性半乳糖性白内障中的酶因素
Enzymatic factors in experimental galactose cataract.
作者信息
LERMAN S
出版信息
Science. 1959 Nov 27;130(3387):1473-4. doi: 10.1126/science.130.3387.1473-a.
Abstract
In the rat lens, glucose-6-phosphate dehydrogenase activity is specifically inhibited by galactose-l-phosphate, both in vitro and in vivo. In galactose-fed animals this inhibition occurs prior to the apparent inhibition of soluble protein synthesis in the ocular lens.
摘要
在大鼠晶状体中，6-磷酸葡萄糖脱氢酶活性在体外和体内均受到1-磷酸半乳糖的特异性抑制。在喂食半乳糖的动物中，这种抑制发生在眼晶状体中可溶性蛋白质合成明显受到抑制之前。
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