MILTON A S
Br J Pharmacol Chemother. 1959 Sep;14(3):323-6. doi: 10.1111/j.1476-5381.1959.tb00251.x.
Further investigation of the effect of tubocurarine on the transport of particles by cilia of the frog oesophagus has confirmed that, when Ringer solution buffered with bicarbonate was used, tubocurarine inhibited the movement in a concentration of 10(-6) g./ml. If, however, Ringer solution with a phosphate buffer was used tubocurarine was without effect. The difference in action is probably due to changes in calcium ion concentration caused by the phosphate in the Ringer solution.
对筒箭毒碱对蛙食管纤毛颗粒转运影响的进一步研究证实,当使用用碳酸氢盐缓冲的任氏液时,筒箭毒碱在浓度为10(-6)克/毫升时会抑制运动。然而,如果使用含磷酸盐缓冲液的任氏液,筒箭毒碱则没有作用。作用的差异可能是由于任氏液中的磷酸盐导致钙离子浓度的变化。