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筒箭毒碱对睫状肌运动的作用。

The action of tubocurarine on ciliary movement.

作者信息

MILTON A S

出版信息

Br J Pharmacol Chemother. 1959 Sep;14(3):323-6. doi: 10.1111/j.1476-5381.1959.tb00251.x.

DOI:10.1111/j.1476-5381.1959.tb00251.x
PMID:14422700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1481749/
Abstract

Further investigation of the effect of tubocurarine on the transport of particles by cilia of the frog oesophagus has confirmed that, when Ringer solution buffered with bicarbonate was used, tubocurarine inhibited the movement in a concentration of 10(-6) g./ml. If, however, Ringer solution with a phosphate buffer was used tubocurarine was without effect. The difference in action is probably due to changes in calcium ion concentration caused by the phosphate in the Ringer solution.

摘要

对筒箭毒碱对蛙食管纤毛颗粒转运影响的进一步研究证实,当使用用碳酸氢盐缓冲的任氏液时,筒箭毒碱在浓度为10(-6)克/毫升时会抑制运动。然而,如果使用含磷酸盐缓冲液的任氏液,筒箭毒碱则没有作用。作用的差异可能是由于任氏液中的磷酸盐导致钙离子浓度的变化。

相似文献

1
The action of tubocurarine on ciliary movement.筒箭毒碱对睫状肌运动的作用。
Br J Pharmacol Chemother. 1959 Sep;14(3):323-6. doi: 10.1111/j.1476-5381.1959.tb00251.x.
2
The action of tubocurarine and acetylcholine on ciliary movement.筒箭毒碱和乙酰胆碱对睫状肌运动的作用。
J Physiol. 1958 May 28;141(3):520-6. doi: 10.1113/jphysiol.1958.sp005993.
3
Action of d-tubocurarine chloride on net flux of water across isolated frog skin.氯化筒箭毒碱对离体蛙皮水净通量的作用。
Science. 1961 May 26;133(3465):1706. doi: 10.1126/science.133.3465.1706.
4
[Study with tubocurarine of the liberation of acetylcholine at the neuromuscular junctions as a function of Ca ion and Mg ion concentrations].[以筒箭毒碱研究神经肌肉接头处乙酰胆碱释放与钙离子和镁离子浓度的关系]
Arch Ital Sci Farmacol. 1961 Apr;11:107-12.
5
The influence of changes in blood pH on the neuromuscular blocking properties of tubocurarine and dimethyl tubocurarine in the cat.血液pH值变化对猫体内筒箭毒碱和二甲基筒箭毒碱神经肌肉阻滞特性的影响。
Acta Anaesthesiol Scand. 1960;4:83-90. doi: 10.1111/j.1399-6576.1960.tb00065.x.
6
Tubocurarine chloride inhibits rod outer segment shedding in the frog retina.
Invest Ophthalmol Vis Sci. 1987 Jun;28(6):1030-2.
7
Scratching movements and facilitation of the scratch reflex produced by tubocurarine in cats.猫中筒箭毒碱引起的抓挠动作及抓挠反射的易化作用。
J Physiol. 1960 Aug;153(1):35-51. doi: 10.1113/jphysiol.1960.sp006517.
8
The combined action of tubocurarine and lightgreen S.F.筒箭毒碱与亮绿S.F.的联合作用
Acta Physiol Pharmacol Neerl. 1962;11:70-5.
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Some data concerning the action of tubocurarine on the nerve centres.
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[Action of thyroxin on the block of the neuromuscular synapse with tubocurarine].[甲状腺素对筒箭毒碱所致神经肌肉突触阻断的作用]
Rev Clin Esp. 1962 Mar 31;84:390-2.

本文引用的文献

1
Ciliary movement and acetylcholine.纤毛运动与乙酰胆碱。
Br J Pharmacol Chemother. 1952 Mar;7(1):67-79. doi: 10.1111/j.1476-5381.1952.tb00691.x.
2
The action of tubocurarine and acetylcholine on ciliary movement.筒箭毒碱和乙酰胆碱对睫状肌运动的作用。
J Physiol. 1958 May 28;141(3):520-6. doi: 10.1113/jphysiol.1958.sp005993.
3
The influence of drugs on ciliary activity.药物对纤毛活动的影响。
J Physiol. 1957 Dec 3;139(2):157-66. doi: 10.1113/jphysiol.1957.sp005883.
4
Acetylcholine and ciliary movement in the gill plates of Mytilus edulis.紫贻贝鳃板中的乙酰胆碱与纤毛运动
Proc R Soc Lond B Biol Sci. 1953 Sep;141(905):445-66. doi: 10.1098/rspb.1953.0053.