Naschitz J E, Yeshurun D, Nash E, Lev L, Shajrawi I, Boss J H
Department of Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel.
Am J Gastroenterol. 1992 Nov;87(11):1665-8.
A solitary cervical metastasis of a typical carcinoid tumor was found in the subcutaneous tissue of an asymptomatic 38-yr-old woman. Investigations failed to disclose the primary site until the 5th yr, when she presented with carcinoid syndrome. Multifocal ileal carcinoid tumors were resected and debulking of abdominal metastases performed. Interferon and somatostatin analogue treatment resulted in remission. Solitary cervical metastasis is an exceedingly rare initial manifestation of a mid-gut carcinoid tumor, and poses a therapeutic dilemma. There are no directions in the literature as to whether a "wait-and-see" approach or exploration surgery is the preferred management when one is confronted by a cervical metastasis of typical carcinoid tumor of unknown primary site.
在一位38岁无症状女性的皮下组织中发现了典型类癌肿瘤的孤立性颈部转移灶。直到第5年，当她出现类癌综合征时，检查才发现原发部位。多灶性回肠类癌肿瘤被切除，并对腹部转移灶进行了减瘤手术。干扰素和生长抑素类似物治疗后病情缓解。孤立性颈部转移是中肠类癌肿瘤极为罕见的初始表现，并且带来了治疗难题。当面对原发部位不明的典型类癌肿瘤的颈部转移时，对于是采用“观察等待”方法还是探索性手术作为首选治疗方案，文献中没有相关指导。
