Fogo A, Superdock K R, Atkinson J B
Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232.
Am J Kidney Dis. 1992 Nov;20(5):513-5. doi: 10.1016/s0272-6386(12)70267-6.
Cocaine abuse has been associated with sudden cardiac death with coronary artery thrombosis with or without underlying vessel disease. Additional vascular beds thus far implicated in cocaine-associated arteriopathy include thoracic and abdominal aorta, and pulmonary, cerebral, and placental vessels; abnormalities include vasospasm, thrombosis, and accelerated atherosclerosis. We report the case of an adult male cocaine user with severe arteriosclerosis of renal vessels, and suggest that cocaine may also affect the renal vasculature.
可卡因滥用与冠状动脉血栓形成导致的心脏性猝死有关,无论是否存在潜在血管疾病。迄今为止,与可卡因相关的动脉病所涉及的其他血管床包括胸主动脉和腹主动脉,以及肺血管、脑血管和胎盘血管;异常情况包括血管痉挛、血栓形成和动脉粥样硬化加速。我们报告了一例成年男性可卡因使用者出现严重肾血管动脉硬化的病例,并提示可卡因可能也会影响肾血管系统。