Calhoun D A
Vascular Biology and Hypertension Program, University of Alabama, Birmingham 35294.
Am J Med Sci. 1992 Nov;304(5):306-11. doi: 10.1097/00000441-199211000-00008.
Primary hypertension is almost twice as prevalent among American blacks as among whites. Causes of this increased prevalence of hypertension remain elusive. Elevation of sympathetic nervous system activity, in part secondary to increased levels of socioeconomic stress, is hypothesized as playing a role. Increased sympathetic nervous system activity may increase peripheral vascular resistance directly or through increased vascular reactivity. Microneurography allows direct measurement of peripheral sympathetic nervous system activity. Application of this technique will allow comparison of sympathetic nervous system activity in black and white subjects and provide additional insight into the role of the sympathetic nervous system in the development of hypertension in blacks.
原发性高血压在美国黑人中的患病率几乎是白人的两倍。高血压患病率增加的原因仍然不明。据推测,交感神经系统活动增强在一定程度上继发于社会经济压力增加,起到了一定作用。交感神经系统活动增强可能直接增加外周血管阻力,或通过增加血管反应性来实现。微神经ography允许直接测量外周交感神经系统活动。应用这项技术将能够比较黑人和白人受试者的交感神经系统活动,并为交感神经系统在黑人高血压发展中的作用提供更多见解。