Kasalický J
Physiol Bohemoslov. 1977 Aug;26(4):373-8.
The regional blood flow through the myocardium of the left ventricle was measured in 11 dogs after ligation of the left anterior descending coronary artery, by means of a local injection of 133Xe depot and precordial detection of its washout 2 hours after ligation. Immediately after ligation the blood flow in the ischaemic area declined considerably but at the same time there was a significant increase of blood flow in the non-ischaemic left ventricular myocardium. The regional flow in the ischaemic and non-ischaemic area increased insignificantly for 2 hrs. These changes were not due to alterations in coronary artery pressure, as the mean arterial pressure declined significantly during the first hour. After temporary ischaemia by ligation of the left anterior descending coronary artery for 2--4 minutes, an intensive reactive hyperaemia developed in the ischaemic region (the blood flow reached 221% of control values on the average) which was the more intensive, the greater the drop of blood flow in the ischaemic area after ligation.
在11只狗身上，通过局部注射133Xe贮库并在结扎左冠状动脉前降支2小时后经心前区检测其洗脱情况，测量左心室心肌的局部血流量。结扎后立即发现，缺血区血流量显著下降，但与此同时，非缺血性左心室心肌的血流量显著增加。缺血区和非缺血区的局部血流量在2小时内无显著增加。这些变化并非由于冠状动脉压力改变所致，因为平均动脉压在最初1小时内显著下降。在结扎左冠状动脉前降支造成2至4分钟的短暂缺血后，缺血区出现强烈的反应性充血（平均血流量达到对照值的221%），结扎后缺血区血流量下降幅度越大，反应性充血就越强烈。
