Hemady R, Zimmerman A, Katzen B W, Karesh J W
Department of Ophthalmology, University of Maryland School of Medicine, Baltimore.
Am J Ophthalmol. 1992 Nov 15;114(5):584-8. doi: 10.1016/s0002-9394(14)74487-3.
Eikenella corrodens is a gram-negative, facultative anaerobic bacillus with specific culture and growth requirements and unusual antibacterial susceptibilities. It has only recently been recognized as a human pathogen. Ocular and adnexal infections with this organism are rare especially in children. We treated two children with orbital cellulitis caused by E. corrodens. One was an 8-year-old boy; the other was an 11-year-old girl. Orbital cellulitis in both patients occurred after an upper respiratory tract infection. Sinusitis and a subperiosteal abscess were present in both patients. Eikenella corrodens and Streptococcus viridans were isolated from the boy; E. corrodens was the sole isolate in the girl. Intravenous ampicillin, prolonged hospitalization, and surgical drainage of the orbit were required to control the infection in both patients. Eikenella corrodens must be considered in the differential diagnosis of orbital cellulitis in children, and ophthalmologists must become familiar with the characteristics of this peculiar organism.
腐蚀埃肯菌是一种革兰氏阴性兼性厌氧杆菌，具有特定的培养和生长要求以及不同寻常的抗菌敏感性。它直到最近才被确认为一种人类病原体。这种微生物引起的眼部和附属器感染很少见，尤其是在儿童中。我们治疗了两名由腐蚀埃肯菌引起眼眶蜂窝织炎的儿童。一名是8岁男孩；另一名是11岁女孩。两名患者的眼眶蜂窝织炎均在上呼吸道感染后发生。两名患者均存在鼻窦炎和骨膜下脓肿。从男孩体内分离出了腐蚀埃肯菌和草绿色链球菌；女孩体内仅分离出腐蚀埃肯菌。两名患者均需要静脉注射氨苄西林、延长住院时间以及对眼眶进行手术引流以控制感染。在儿童眼眶蜂窝织炎的鉴别诊断中必须考虑到腐蚀埃肯菌，眼科医生必须熟悉这种特殊微生物的特征。
