Redondo Granado M J, Alvarez Guisasola F J, Gómez Martín I, Bobillo del Amo H, Blanco Quirós A, Mateos Otero J J
Departamento de Pediatría, Hospital Clínico Universitario de Valladolid.
An Esp Pediatr. 1992 Sep;37(3):233-7.
Between 1985 and 1990, 45 children were studied in an inpatient basis hospital because of cervical lymphadenopathy. This was the most important clinical sign in these patients. Forty-three had true adenitis. In the others, one was submaxillitis and one a sarcoma. The age range was from 2.1 to 13.3 years. Seven children (16%) had neoplastic adenitis (2 papillary carcinoma of the thyroid, 4 Hodgkin's lymphoma and one non-Hodgkin's lymphoma). Thirty-six patients had benign disorders (18 mononucleosis infections, 7 nonspecific adenitis, 5 infections of mycobacteria, 2 of toxoplasma and 2 of rickettsia, one cervical Whipple and one desmopathic adenitis). We did no find any differences related to age or morphological characteristics of the lymph nodes. The evolution time in patients with malignant tumors was 16.4 weeks and 9.6 weeks in the benign group. All of the cases with supraclavicular location had a lymphoma. The mean LDH in patients with malignant tumors was 214 U/L and 614 U/L in those with non-malignant tumors (p < 0.01).
1985年至1990年间,45名因颈部淋巴结病而在住院基础医院接受研究的儿童。这是这些患者最重要的临床体征。43例为真性腺炎。在其他病例中,1例为颌下腺炎,1例为肉瘤。年龄范围为2.1至13.3岁。7名儿童(16%)患有肿瘤性腺炎(2例甲状腺乳头状癌、4例霍奇金淋巴瘤和1例非霍奇金淋巴瘤)。36例患者患有良性疾病(18例单核细胞增多症感染、7例非特异性腺炎、5例分枝杆菌感染、2例弓形虫感染和2例立克次体感染、1例颈部惠普尔病和1例致密性腺炎)。我们未发现与年龄或淋巴结形态特征相关的任何差异。恶性肿瘤患者的病程为16.4周,良性组为9.6周。所有锁骨上部位的病例均患有淋巴瘤。恶性肿瘤患者的平均乳酸脱氢酶为214 U/L,非恶性肿瘤患者为614 U/L(p<0.01)。