Mammoliti S, Bruzzone M, Chiara S, Vidali A, Miglio L, Fontana V, Oliva C, Compora E, Giuntini P, Centonze M
National Institute of Cancer Research, Genoa, Italy.
Anticancer Res. 1992 Sep-Oct;12(5):1415-8.
In 221 patients with FIGO stage I and II endometrial carcinoma, the impact on survival of age at diagnosis, menopausal status, FIGO stage, myometrial invasion, tumor grade and histology was evaluated by univariate and multivariate analysis. At a median follow-up of 50 months (range 45-210), 42 patients had died, and therefore overall survival was 81% (179/221). Univariate analysis showed that age, menopausal status and histology did not influence survival, whereas FIGO stage, myometrial invasion and tumor grade were important prognostic factors. Multivariate analysis showed that tumor grade had a significant and independent impact on survival and confirmed that FIGO stage is the most important parameter influencing survival.
在221例国际妇产科联盟（FIGO）I期和II期子宫内膜癌患者中，通过单因素和多因素分析评估了诊断时年龄、绝经状态、FIGO分期、肌层浸润、肿瘤分级和组织学对生存的影响。中位随访50个月（范围45 - 210个月）时，42例患者死亡，因此总生存率为81%（179/221）。单因素分析显示，年龄、绝经状态和组织学不影响生存，而FIGO分期、肌层浸润和肿瘤分级是重要的预后因素。多因素分析显示，肿瘤分级对生存有显著且独立的影响，并证实FIGO分期是影响生存的最重要参数。
