微滤泡性甲状腺腺瘤与先天性甲状腺肿性甲状腺功能减退症

Microfollicular thyroid adenoma and congenital goitrous hypothyroidism.

作者信息

Alabbasy A J, Delbridge L, Eckstein R, Cowell C, Silink M

机构信息

Ray Williams Institute of Paediatric Endocrinology, Royal Alexandra Hospital for Children, Camperdown, NSW, Australia.

出版信息

Arch Dis Child. 1992 Oct;67(10):1294-5. doi: 10.1136/adc.67.10.1294.

DOI:10.1136/adc.67.10.1294

PMID:1444533

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1793925/

Abstract

Three patients with congenital goitrous hypothyroidism are reported. They were treated with adequate thyroxine replacement and developed well defined microfollicular thyroid adenomas despite being euthyroid clinically and biochemically throughout their clinical course. Patients with congenital goitrous hypothyroidism appear to be at increased risk of developing thyroid adenoma in childhood despite the use of replacement thyroxine treatment in physiological doses.

摘要

报告了3例先天性甲状腺肿性甲状腺功能减退症患者。他们接受了足够的甲状腺素替代治疗，尽管在整个临床过程中临床和生化指标均处于甲状腺功能正常状态，但仍出现了界限清晰的微滤泡性甲状腺腺瘤。尽管使用生理剂量的甲状腺素替代治疗，先天性甲状腺肿性甲状腺功能减退症患者在儿童期发生甲状腺腺瘤的风险似乎增加。