健康新生儿间歇性导管通畅：彩色多普勒血流图显示
Intermittent ductal patency in healthy newborn infants: demonstration by colour Doppler flow mapping.
作者信息
Lim M K, Hanretty K, Houston A B, Lilley S, Murtagh E P
机构信息
Department of Cardiology, Royal Hospital For Sick Children, Yorkhill, Glasgow.
出版信息
Arch Dis Child. 1992 Oct;67(10 Spec No):1217-8. doi: 10.1136/adc.67.10_spec_no.1217.
Colour Doppler flow mapping was used to determine the time of closure of the arterial duct in 51 healthy newborn infants. Initial time of closure corresponded with previous reports: 20% on the first day, 82% by the second day, 96% by the third day, and 100% by the fourth day. Twenty infants were delivered by caesarean section and followed up for seven days even if the duct had apparently closed; in six intermittent patency was demonstrated with flow in the third, fourth or fifth day, although earlier functional closure had been observed. All were found to be closed on the sixth and seventh days. It is necessary to be aware of the phenomenon of intermittent closure in any study determining or assessing the effect of any intervention on ductal patency.
采用彩色多普勒血流成像技术测定了51例健康新生儿动脉导管关闭的时间。首次关闭时间与先前报道相符：第1天为20%，第2天为82%，第3天为96%，第4天为100%。20例经剖宫产分娩的婴儿，即使动脉导管明显已关闭，仍随访7天；其中6例在第3、4或5天出现间歇性通畅并有血流，尽管较早时已观察到功能性关闭。所有病例在第6天和第7天均发现已关闭。在任何确定或评估任何干预措施对动脉导管通畅性影响的研究中，都有必要了解间歇性关闭现象。
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