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[阿莫西林克拉维酸钾干混悬剂治疗儿童由机会致病菌引起的化脓性炎症性疾病疗效的临床实验室评估]

[A clinico-laboratory assessment of the efficacy of an Augmentin suspension in treating children with suppurative-inflammatory diseases caused by opportunistic bacteria].

作者信息

Savitskaia K I, Nekhorosheva A G, Skala L Z, Nasonov V N, Solodilova O E, Shanina A G, Dutova E N

出版信息

Antibiot Khimioter. 1992 Sep;37(9):29-33.

PMID:1444666
Abstract

Augmentin suspension (amoxycillin+clavulanic acid) was estimated in clinico-laboratory studies with respect to children suffering from pyoinflammatory diseases of various localization and its high efficacy was shown. Good and satisfactory results were recorded in 96.3 per cent of the cases in the treatment (monotherapy) and afterwards in the patients, adverse reactions such as nausea and vomiting being recorded only in 1 patient. The therapy with augmentin led to normalization of the microflora of the upper respiratory tract mucosa and a 1.5-fold increase in the neutrophil engulfment index.

摘要

在针对患有不同部位脓性炎症疾病的儿童进行的临床实验室研究中,对阿莫西林克拉维酸钾混悬液(阿莫西林+克拉维酸)进行了评估,结果显示其具有高效性。在治疗(单一疗法)的病例中,96.3%取得了良好和满意的效果,之后在患者中,仅1例记录到恶心和呕吐等不良反应。阿莫西林克拉维酸钾治疗使上呼吸道黏膜微生物群恢复正常,中性粒细胞吞噬指数提高了1.5倍。

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