Landry F J, Parker J M, Phillips Y Y
Department of Medicine, Walter Reed Army Medical Center, Washington, DC 20307-5001.
Arch Intern Med. 1992 Nov;152(11):2305-8.
Although cardiopulmonary resuscitation (CPR) has been shown to be most effective in a monitored setting, previous studies have focused primarily on patients with acute cardiac events rather than chronic progressive disease. This study examined the outcome of CPR in the medical and surgical intensive care units where patients often have acute illness superimposed on chronic underlying conditions.
We present a retrospective chart review of all patients undergoing CPR in medical and surgical intensive care units during a 2-year period.
One hundred fourteen charts were reviewed. Patient mean age was 59 years. The primary underlying disease was malignancy in 29 (25%), vascular disease in 20 (18%), chronic liver disease in eight (7%), end-stage renal disease in six (5%), chronic obstructive pulmonary disease in five (5%), and other conditions in 46 (40%) patients. Although 50 (44%) of the patients were initially resuscitated, only six (5%) ultimately survived to hospital discharge. Only one of 29 patients with malignancy and one of 39 septic patients survived. Age, sex, and Acute Physiology and Chronic Health Evaluation II scores were similar among survivors and nonsurvivors. Furthermore, four of the six survivors died within 1 year of discharge, and the two others had severe disabilities.
Patients with chronic medical conditions undergoing CPR even in an intensive care unit setting seldom survive to hospital discharge. Even among the few survivors, the near term prognosis is poor. Therefore, the decision to perform CPR should take into account underlying chronic medical conditions and not merely the setting of the arrest.
尽管心肺复苏术(CPR)已被证明在监测环境中最为有效,但先前的研究主要集中于急性心脏事件患者,而非慢性进行性疾病患者。本研究调查了在内科和外科重症监护病房中接受心肺复苏术的患者的结局,这些病房中的患者通常在慢性基础疾病之上叠加有急性疾病。
我们对两年期间在内科和外科重症监护病房接受心肺复苏术的所有患者进行了回顾性病历审查。
审查了114份病历。患者平均年龄为59岁。主要基础疾病为恶性肿瘤29例(25%)、血管疾病20例(18%)、慢性肝病8例(7%)、终末期肾病6例(5%)、慢性阻塞性肺疾病5例(5%),其他情况46例(40%)。尽管50例(44%)患者最初复苏成功,但最终仅6例(5%)存活至出院。29例恶性肿瘤患者中仅1例存活,39例脓毒症患者中仅1例存活。幸存者和非幸存者的年龄、性别以及急性生理学与慢性健康状况评分II相似。此外,6名幸存者中有4人在出院后1年内死亡,另外2人有严重残疾。
即使在重症监护病房环境中接受心肺复苏术的慢性疾病患者也很少能存活至出院。即使在少数幸存者中,近期预后也很差。因此,决定是否进行心肺复苏术应考虑基础慢性疾病,而不仅仅是心脏骤停的环境。