Koch B M, Wu C M, Randolph J, Eng G D
Department of Physical Medicine and Rehabilitation, Children's National Medical Center, Washington, DC 20010-2970.
Arch Phys Med Rehabil. 1992 Nov;73(11):1104-6.
Heterotopic ossification is the formation of ectopic bone in soft tissue, and has been reported as a rare complication in pediatric burn patients. At our hospital, two 86% body surface area burn patients developed heterotopic ossification in the shoulder, elbows, distal femur, proximal tibia, fibula, and ribs approximately four months after the burn injury. These two rare and unusual cases are presented documenting the clinical involvement, radiological studies, laboratory data, as well as treatment of their heterotopic ossification. Discussion will focus on the incidence, diagnosis, pathophysiology, and treatment of heterotopic ossification in burn patients and how this information relates to the specific diagnosis and management of the complication of heterotopic ossification in the burn child.
异位骨化是指在软组织中形成异位骨,据报道这是小儿烧伤患者中一种罕见的并发症。在我们医院,两名烧伤面积达86%体表面积的患者在烧伤后约四个月,在肩部、肘部、股骨远端、胫骨近端、腓骨和肋骨处出现了异位骨化。本文展示了这两例罕见且特殊的病例,记录了其临床情况、影像学检查、实验室数据以及异位骨化的治疗情况。讨论将聚焦于烧伤患者异位骨化的发生率、诊断、病理生理学和治疗,以及这些信息与烧伤儿童异位骨化并发症的具体诊断和管理的关系。