Ziglio G, Beltramelli G, Montanari L, Cingolani E
Istituto di Igiene, Università di Milano, Italy.
Boll Chim Farm. 1992 May;131(5):193-8.
Some volatile halogenated hydrocarbons have been found in commercial large volume parenterals (LVPs) prepared from untreated or treated (disinfected) water. To monitor the presence of volatile halogenated hydrocarbons in the source water and also in the water for injections, a low cost and sufficiently simple procedure has been developed, specifically for the following components: 1,1,1 trichloroethane, 1,1,2 trichloroethylene, 1,1,2,2 tetrachloroethylene, carbon tetrachloride, chloroform, dichlorobromomethane and dibromochloromethane. A Head-space technique coupled with ECD-gaschromatography was used. The procedure is thoroughly discussed in the article, including the results of a ring test for a preliminary validation of this method.
在由未经处理或经过处理（消毒）的水制备的商业大容量注射剂（LVP）中发现了一些挥发性卤代烃。为监测源水和注射用水中挥发性卤代烃的存在情况，已开发出一种低成本且足够简单的程序，专门用于检测以下成分：1,1,1 - 三氯乙烷、1,1,2 - 三氯乙烯、1,1,2,2 - 四氯乙烯、四氯化碳、氯仿、二氯溴甲烷和二溴氯甲烷。采用了顶空技术结合电子捕获检测器气相色谱法。本文对该程序进行了全面讨论，包括对该方法进行初步验证的循环测试结果。
