Denys A, Machlański T, Bialek J, Mrozicki S
Zentralbl Bakteriol Orig B. 1977 Jan;164(1-2):85-9.
The aim of this report was to indicate the correlation between chemical structure and antiviral activity of some biguanide derivatives obtained according to Monsanto Chemicals Ltd. Neth. Appl. 289. 283. The studies were carried out on the culture of monkey kidney cells infected with parainfluenza Sendai virus and on the mice infected with influenza virus. The increase of antiviral activities of N-Phenylbiguanide and N-p-Ethoxyphenylbiguanide was estimated.
本报告的目的是指出根据孟山都化学有限公司荷兰专利申请289,283所获得的某些双胍衍生物的化学结构与抗病毒活性之间的相关性。研究是在感染仙台副流感病毒的猴肾细胞培养物以及感染流感病毒的小鼠身上进行的。评估了N-苯基双胍和N-对乙氧基苯基双胍抗病毒活性的增强情况。
