Yuguchi Y, Inoue M, Takiguchi Y, Kohno N, Okita S, Tojima H, Yamaguchi T, Tanabe N, Nagao K, Kuriyama T
Department of Chest Medicine, School of Medicine, Chiba University, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Sep;30(9):1711-8.
ECG-gated spin-echo MR images of the chest were obtained in two patients with primary pulmonary hypertension (PPH). In transverse section at the level of the right main pulmonary artery (rPA), flow signals in the rPA were quantitatively evaluated, and the correlations with MR signal intensity of intravascular flow and data of routine clinical examinations and the severity of clinical manifestations were studied. In one case, the signal intensity of flowing blood markedly increased with exacerbation of hypoxemia and other clinical manifestations. However, in the other case with a stable course, the signal intensity of intravascular flow did not change significantly. Increase of flow signal in the rPA can reflect decrease of flow velocity that may be cause by a state of high pulmonary vascular resistance or low cardiac output. Therefore, it is suggested that MRI is a useful modality to evaluate the severity of disturbance of the pulmonary circulation in PPH.
对两名原发性肺动脉高压（PPH）患者进行了胸部心电图门控自旋回波磁共振成像检查。在右主肺动脉（rPA）水平的横断面上，对rPA中的血流信号进行了定量评估，并研究了其与血管内血流磁共振信号强度、常规临床检查数据以及临床表现严重程度之间的相关性。在一例患者中，随着低氧血症和其他临床表现的加重，流动血液的信号强度明显增加。然而，在另一例病情稳定的患者中，血管内血流信号强度没有明显变化。rPA中血流信号的增加可反映流速的降低，这可能是由高肺血管阻力或低心输出量状态引起的。因此，提示磁共振成像（MRI）是评估PPH患者肺循环障碍严重程度的一种有用方法。
