Horbenko H P
Ukr Biokhim Zh (1978). 1992 Jul-Aug;64(4):108-12.
Lipid peroxidation induced by methemoglobin in liposomes prepared from lecithin, cardiolipin and their mixtures has been investigated. Using absorption spectroscopy technique it was shown that in the bilayers with low initial oxidation methemoglobin caused the formation of diene conjugates. In the bilayers with high degree of oxidation protein activated cleavage of the available fatty acid hydroperoxides. Hydroperoxides were found to induce the reduction of methemoglobin absorption in the Soret band.
已对由卵磷脂、心磷脂及其混合物制备的脂质体中高铁血红蛋白诱导的脂质过氧化进行了研究。使用吸收光谱技术表明，在初始氧化程度较低的双层中，高铁血红蛋白导致二烯共轭物的形成。在氧化程度较高的双层中，蛋白质激活了可用脂肪酸氢过氧化物的裂解。发现氢过氧化物会导致高铁血红蛋白在索雷特带的吸收降低。
