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一例多发性骨髓瘤患者尿液中的脱落“骨髓瘤细胞”

Exfoliated 'myeloma cells' in the urine of a case of multiple myelomatosis.

作者信息

PROWSE C M, BLECHER T E

出版信息

J Clin Pathol. 1962 Mar;15(2):136-40. doi: 10.1136/jcp.15.2.136.

Abstract

The clinical features and special investigations in a case of multiple myelomatosis are described. The finding of exfoliated ;myeloma cells' in the urine of this case is thought to be unique, these cells closely resembling the myeloma cells seen in the bone marrow. The necropsy findings indicated that the origin of the cells was from a plasma cell infiltrate of the kidneys rather than from isolated plasmacytoma of any part of the urinary tract.

摘要

本文描述了一例多发性骨髓瘤患者的临床特征及特殊检查结果。该病例尿液中发现脱落的“骨髓瘤细胞”,这一发现被认为是独特的,这些细胞与骨髓中所见的骨髓瘤细胞极为相似。尸检结果表明,这些细胞起源于肾脏的浆细胞浸润,而非来自泌尿道任何部位的孤立性浆细胞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94a6/480361/4571ee7d587c/jclinpath00067-0039-a.jpg

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本文引用的文献

1
DOMZ CA: Renal patterns in myeloma.
Ann Intern Med. 1960 Jan;52:44-54. doi: 10.7326/0003-4819-52-1-44.
2
A review of fifty-one cases of multiple myeloma; emphasis on pneumonia and other infections as complications.
AMA Arch Intern Med. 1959 Feb;103(2):173-83. doi: 10.1001/archinte.1959.00270020001001.
3
Exfoliative cytology of urinary sediments; a review of 2,829 cases.
Cancer. 1958 Jan-Feb;11(1):127-37. doi: 10.1002/1097-0142(195801/02)11:1<127::aid-cncr2820110124>3.0.co;2-w.

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