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[左旋冠状动脉异常起源:临床、血管造影及预后方面。附30例报告]

[Abnormal origin of the left circumflex coronary artery: clinical, angiographic and prognostic aspects. Apropos of 30 cases].

作者信息

Leroy F, Germain S, Bauters C, Lablanche J M, Bertrand M E

机构信息

Service de cardiologie B, hôpital cardiologique, université de Lille II.

出版信息

Arch Mal Coeur Vaiss. 1992 Jul;85(7):993-9.

PMID:1449347
Abstract

The object of this study of 30 patients with an anomalous origin of the left circumflex coronary artery was to define the clinical and angiographic features of this condition and to assess its influence on morbidity and survival. The 30 patients were 24 men and 6 women with ages ranging from 29 to 76 years. An anomalous origin of the left circumflex coronary artery should be suspected when two angiographic signs are present: firstly, the visualisation of a spur of opacification in the 30 degrees LAO view of left ventriculography, present in 93% or our patients; secondly, during selective left coronary angiography in the transverse view, an ascular zone is observed where the normal left circumflex artery should be. Confirmation of the diagnosis depends on opacification of the left circumflex arising from the right anterior sinus of Valsalva with a separate (37%) or common (23%) orifice with the right coronary artery or arising from a proximal segment of the right coronary artery/(40%). Five patients (17%) had a significant stenosis of the anomalous left circumflex coronary artery but this was always associated with lesions of the other coronary narrowing was observed. Of these patients, one had electrocardiographic signs of myocardial ischaemia and no other cause apart from the anomalous origin of the left circumflex to explain this ischaemia. The 30 patients were followed up for an average of 6.1 +/- 3.9 years. During this period, 1 cardiac death, 1 infarction, 5 cases of angina, 4 coronary bypass procedures, and 6 coronary angioplasties were observed. Nine patients (30%) had no cardiac event during follow-up.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本研究针对30例左旋支冠状动脉异常起源患者,旨在明确该病症的临床及血管造影特征,并评估其对发病率和生存率的影响。30例患者中,男性24例,女性6例,年龄在29至76岁之间。当出现两个血管造影征象时,应怀疑左旋支冠状动脉异常起源:其一,左心室造影30度左前斜位可见造影剂充盈的 spur,93%的患者存在此征象;其二,在横位选择性左冠状动脉造影时,可观察到正常左旋支动脉所在位置出现血管区域缺失。诊断的确立取决于左旋支动脉由瓦尔萨尔瓦右前窦发出,与右冠状动脉分别开口(37%)或共同开口(23%),或由右冠状动脉近端发出(40%)并显影。5例患者(17%)异常的左旋支冠状动脉存在明显狭窄,但这总是与其他冠状动脉病变相关,未观察到单纯狭窄情况。其中1例患者有心肌缺血的心电图表现,除左旋支异常起源外无其他原因可解释该缺血情况。30例患者平均随访6.1±3.9年。在此期间,观察到1例心源性死亡、1例心肌梗死、5例心绞痛、4例冠状动脉搭桥手术和6例冠状动脉成形术。9例患者(30%)在随访期间无心脏事件发生。(摘要截选至250字)

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