Alreshaid Abdulrahman A, Powers William J
Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Neurology. 2003 Sep 23;61(6):831-3. doi: 10.1212/01.wnl.0000081047.22043.ab.
The authors retrospectively analyzed 25 patients who had a nondiagnostic brain biopsy for clinically suspected primary CNS angiitis to determine the effect of immunosuppressive therapy on 1-year outcome. Good outcome was seen in 6 of 10 treated patients and in 8 of 15 untreated patients (p= 0.93). These findings do not indicate that the addition of immunosuppressive therapy significantly enhances outcome of patients with clinically suspected primary angiitis of the CNS and a nondiagnostic brain biopsy.
作者回顾性分析了25例因临床怀疑原发性中枢神经系统血管炎而进行非诊断性脑活检的患者，以确定免疫抑制治疗对1年预后的影响。10例接受治疗的患者中有6例预后良好，15例未接受治疗的患者中有8例预后良好（p = 0.93）。这些结果并不表明添加免疫抑制治疗能显著改善临床怀疑原发性中枢神经系统血管炎且脑活检未确诊的患者的预后。
