丙型肝炎病毒及非甲非丙型慢性肝炎的α-2b干扰素疗法
Interferon alpha 2-b therapy of HCV and nonBnonC chronic hepatitis.
作者信息
Gargiulo M, Tarquini P, Di Ottavio L, Lattanzi E, De Nigris-Urbani A
机构信息
Sezione Malattie Infettive, Ospedale Civile G. Mazzini, Teramo, Italy.
出版信息
Arch Virol Suppl. 1992;4:304-5. doi: 10.1007/978-3-7091-5633-9_68.
PMID:1450709
Abstract
Twenty-four patients with HCV and NonBNonC chronic hepatitis--4 with HIV coinfection--were treated with r-IFN alpha for at least six months. In this period 62.5% of patients show a normalization of ALT but not a sustained remission. Non-responders have histologically more severe and long-lasting chronic hepatitis.
摘要
24例丙型肝炎病毒（HCV）感染及非乙非丙型慢性肝炎患者——其中4例合并人类免疫缺陷病毒（HIV）感染——接受了至少6个月的重组α干扰素（r-IFNα）治疗。在此期间，62.5%的患者谷丙转氨酶（ALT）恢复正常，但未实现持续缓解。无应答者在组织学上患有更严重且病程更长的慢性肝炎。
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