van Dijck J A, Verbeek A L, Hendriks J H, Holland R
National Expert and Training Centre for Breast Cancer Screening, St Radboud University Hospital, Nijmegen, The Netherlands.
Br J Radiol. 1992 Nov;65(779):971-6. doi: 10.1259/0007-1285-65-779-971.
Two-view mammography is generally preferred as an initial screening examination because the number of missed carcinomas and false positive results in one-view mammography is considered too large. The present review was performed to assess the difference in screening quality between one- and two-view mammography. Nineteen previous studies were reviewed and differences in sensitivity as well as specificity between two-view and one-view mammography were calculated. The results ranged from -5.7% to 19.4% (median 3.9%), and 2.7% to 36.1% (median 14.8%), respectively, and indicate a higher screening quality of two-view mammography. However, in the studies considered there is a large variation in study population, screening tests used and assessment of disease outcome, which makes the numerical results less conclusive. None of the studies provided adequate information for deciding whether two-view mammography in baseline screening for breast cancer is preferable to one-view mammography. If a screening programme using one-view mammography has already achieved high sensitivity and specificity, the value of an additional craniocaudal view is only marginal.
通常更倾向于采用双视角乳腺钼靶检查作为初始筛查手段，因为单视角乳腺钼靶检查中漏诊癌和假阳性结果的数量被认为过多。进行本综述旨在评估单视角和双视角乳腺钼靶检查在筛查质量上的差异。回顾了此前的19项研究，并计算了双视角和单视角乳腺钼靶检查在敏感性以及特异性方面的差异。结果分别为-5.7%至19.4%（中位数为3.9%），以及2.7%至36.1%（中位数为14.8%），这表明双视角乳腺钼靶检查具有更高的筛查质量。然而，在所纳入的研究中，研究人群、所使用的筛查测试以及疾病结局评估存在很大差异，这使得数值结果的结论性较差。没有一项研究提供足够的信息来判定在乳腺癌基线筛查中双视角乳腺钼靶检查是否优于单视角乳腺钼靶检查。如果使用单视角乳腺钼靶检查的筛查项目已经实现了高敏感性和特异性，那么额外增加头足位视角的价值仅微乎其微。
