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[自闭症儿童大脑偏侧化障碍的证明:经颅脉冲多普勒对听觉反应性的研究]

[Demonstration of cerebral lateralisation disorder in autistic children: study of auditory reactivity by transcranial pulsed Doppler].

作者信息

Bruneau N, Garreau B, Dourneau M C, Barthélémy C, Pourcelot L, Lelord G

机构信息

INSERM U316, Explorations fonctionnelles psychopathologiques, CHU Bretonneau, Tours.

出版信息

C R Seances Soc Biol Fil. 1992;186(1-2):139-44.

PMID:1450987
Abstract

Transcranial Doppler Ultrasonographic recordings of the middle cerebral arteries were performed on children with autistic behavior (AUT), compared to retarded children without autistic behavior (NON-AUT) and normal children (NOR). Blood flow measurements (resistance index) were performed at rest and during auditory stimulations. Compared to NOR and NON-AUT, significant differences of the resistance index were found in AUT on the left side, thus suggesting differences in metabolic mechanisms evoked by auditory stimulations. This result confirms the hypothesis of abnormal development of cerebral lateralization in autism.

摘要

对患有自闭症行为(AUT)的儿童进行大脑中动脉的经颅多普勒超声记录,并与无自闭症行为的智力迟钝儿童(NON - AUT)和正常儿童(NOR)进行比较。在静息状态和听觉刺激期间进行血流测量(阻力指数)。与NOR和NON - AUT相比,发现AUT左侧的阻力指数存在显著差异,这表明听觉刺激引起的代谢机制存在差异。这一结果证实了自闭症中大脑偏侧化异常发育的假设。

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