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Photoreactivity of 5-iodouracil-containing telomeric DNA.

作者信息

Xu Yan, Sugiyama Hiroshi

机构信息

Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda, Tokyo 101-0062, Japan.

出版信息

Nucleic Acids Res Suppl. 2003(3):71-2. doi: 10.1093/nass/3.1.71.

Abstract

The photoreaction of 5-iodouracil-((I)U)-containing telomeric oligonucleotides in parallel or antiparallel structures, generated in the presence of K+ or Na+ ions, was investigated. It was found that the photoreactivity of telomeric DNA depends on the differences in the quadruplex conformations in the presence of K+ or Na+ ions.

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