蛙胃黏膜从黏膜下层摄取钾离子及酸分泌速率。

Uptake of K+ by frog gastric mucosa from submucosal side and acid secretory rate.

作者信息

Takeguchi N, Horikoshi I, Hattori M

出版信息

Am J Physiol. 1977 Mar;232(3):E294-7. doi: 10.1152/ajpendo.1977.232.3.E294.

DOI:10.1152/ajpendo.1977.232.3.E294

Abstract

The K+ content in frog gastric mucosa (K+) was measured as a function of the submucosal K+ concentration ([K+sm]) in the absence of K+ on the mucosal side. The (K+) in HCO3- buffer with 95% O2-5% CO2 gas showed that the removal of external K+ induced a 27% K+ loss from the control value of 5 mM K+sm, that there was no linear relation between (K+) and [K+sm, and that the change in the (K+) versus the [K+sm] was hyperbolic, indicating that there are two different types of K+ in the mucosa: bound and free K+.

摘要

在黏膜侧无钾离子的情况下，测量了青蛙胃黏膜中的钾离子含量（K⁺）作为黏膜下钾离子浓度（[K⁺sm]）的函数。在含95% O₂ - 5% CO₂气体的HCO₃⁻缓冲液中的（K⁺）表明，去除外部钾离子会导致从5 mM K⁺sm的对照值损失27%的K⁺，（K⁺）与[K⁺sm]之间不存在线性关系，并且（K⁺）相对于[K⁺sm]的变化是双曲线的，这表明黏膜中存在两种不同类型的钾离子：结合态和游离态钾离子。