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[特应性皮炎。激发因素谱及其有效减少和消除的可能性]

[Atopic eczema. Spectrum of provocation factors and possibilities for their effective reduction and elimination].

作者信息

Fischer S, Ring J, Abeck D

机构信息

Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München, Munich.

出版信息

Hautarzt. 2003 Oct;54(10):914-24. doi: 10.1007/s00105-003-0557-7.

DOI:10.1007/s00105-003-0557-7
PMID:14513237
Abstract

Atopic eczema forms together with extrinsic bronchial asthma and allergic rhinoconjunctivitis the classical atopic triad. Genetic predisposition is the crucial pathogenetic factor. The combination of genetic disposition and provocation factors leads to the clinical appearance of skin disease. In addition to therapy adjusted to the stage of the disease, modern management should include a search for relevant trigger factors and then their avoidance to reduce or even prevent flares of the disease. The spectrum of provocation factors ranges from simple measures such as appropriate clothing up to specific measures such as indoor aeroallergen reduction measures.

摘要

特应性皮炎与外源性支气管哮喘和过敏性鼻结膜炎共同构成经典的特应性三联征。遗传易感性是关键的致病因素。遗传倾向与诱发因素相结合导致皮肤病的临床表现。除了根据疾病阶段调整治疗外,现代管理还应包括寻找相关触发因素,然后避免这些因素以减少甚至预防疾病发作。诱发因素的范围从简单措施如穿着合适的衣物到具体措施如减少室内空气过敏原措施。

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引用本文的文献

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本文引用的文献

1
Silver-coated textiles reduce Staphylococcus aureus colonization in patients with atopic eczema.
Dermatology. 2003;207(1):15-21. doi: 10.1159/000070935.
2
Orange-induced skin lesions in patients with atopic eczema: evidence for a non-IgE-mediated mechanism.
Acta Derm Venereol. 2003;83(1):44-8. doi: 10.1080/00015550310002701.
3
Effect of mattress encasings on atopic dermatitis outcome measures in a double-blind, placebo-controlled study: the Dutch mite avoidance study.床垫套对特应性皮炎结局指标影响的双盲、安慰剂对照研究:荷兰螨虫回避研究
J Allergy Clin Immunol. 2002 Sep;110(3):500-6. doi: 10.1067/mai.2002.126791.
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Influence of probiotic supplemented infant formula on composition of plasma lipids in atopic infants.
J Nutr Biochem. 2002 Jun;13(6):364-369. doi: 10.1016/s0955-2863(02)00185-7.
5
[Nutritional status of adult patients with atopic dermatitis].[特应性皮炎成年患者的营养状况]
Hautarzt. 2002 Mar;53(3):183-8. doi: 10.1007/s00105-001-0326-4.
6
Stressful life events promote the manifestation of asthma and atopic diseases.压力大的生活事件会促使哮喘和过敏性疾病的显现。
Clin Exp Allergy. 2002 Feb;32(2):256-63. doi: 10.1046/j.1365-2222.2002.01282.x.
7
Effectiveness of and compliance to intervention measures in reducing house dust and cat allergen levels.干预措施在降低室内灰尘和猫过敏原水平方面的有效性及依从性。
Ann Allergy Asthma Immunol. 2002 Jan;88(1):52-8. doi: 10.1016/s1081-1206(10)63592-2.
8
Probiotics during pregnancy and breast-feeding might confer immunomodulatory protection against atopic disease in the infant.
J Allergy Clin Immunol. 2002 Jan;109(1):119-21. doi: 10.1067/mai.2002.120273.
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Immunotherapy in allergic rhinitis.变应性鼻炎的免疫疗法
Allerg Immunol (Paris). 2001 Oct;33(8):323-6.
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Optimal management of atopic dermatitis.
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