Fischer S, Ring J, Abeck D
Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München, Munich.
Hautarzt. 2003 Oct;54(10):914-24. doi: 10.1007/s00105-003-0557-7.
Atopic eczema forms together with extrinsic bronchial asthma and allergic rhinoconjunctivitis the classical atopic triad. Genetic predisposition is the crucial pathogenetic factor. The combination of genetic disposition and provocation factors leads to the clinical appearance of skin disease. In addition to therapy adjusted to the stage of the disease, modern management should include a search for relevant trigger factors and then their avoidance to reduce or even prevent flares of the disease. The spectrum of provocation factors ranges from simple measures such as appropriate clothing up to specific measures such as indoor aeroallergen reduction measures.
特应性皮炎与外源性支气管哮喘和过敏性鼻结膜炎共同构成经典的特应性三联征。遗传易感性是关键的致病因素。遗传倾向与诱发因素相结合导致皮肤病的临床表现。除了根据疾病阶段调整治疗外,现代管理还应包括寻找相关触发因素,然后避免这些因素以减少甚至预防疾病发作。诱发因素的范围从简单措施如穿着合适的衣物到具体措施如减少室内空气过敏原措施。