[已知风险因素的成年人群中腹主动脉瘤的发生率]

[Frequency of abdominal aortic aneurysms in adult population with known risk factors].

作者信息

Valdés Francisco, Sepúlveda Nelson, Krämer Albrecht, Mertens Renato, Bergoeing Michel, Mariné Leopoldo, Alcarte Miguel, Carbonell Juan P, Burgos Luis, Lagos Marcelo, Fava Mario, Wong Carlos, Vergara Jeanette

机构信息

Departamento de Enfermedades Cardiovasculares, División de Cirugía, Hospital Clínico, Facultad de Medicina, Pontificia Universidad Católica de Chile.

出版信息

Rev Med Chil. 2003 Jul;131(7):741-7.

PMID:14513694

Abstract

BACKGROUND

The incidence of abdominal aortic aneurysms has increased. Its predisposing factors are smoking, high blood pressure and dislipidemia. Progressive aneurysmal enlargement may lead to its rupture, which is associated to a mortality rate above 80%.

AIM

To assess the prevalence of abdominal aortic aneurysms in Chilean subjects with cardiovascular risk factors.

SUBJECTS AND METHODS

Through announcements in open media we invited individuals aged over 60 years, who smoked, had hypertension and/or had occlusive arterial disease, to participate in a study that included medical history and physical examination. An aortic ultrasound was performed in all subjects in whom the aorta was not palpable or there was a suspicion of dilatation. Aortic diameter over 3 cm was considered aneurysmal.

RESULTS

Three hundred fifty six subjects aged 67.1 +/- 6.7 years, (73.9% males), were evaluated. The study group included 62% hypertensives, 39% with abnormal lipids and 46% smokers. Known coronary heart disease or peripheral arterial diseases were present in 14% and 10%, respectively. Ultrasound was required in 159 subjects. Aneurysms were detected in 21 persons (5.9%), 7.6% in males and 1.1% in females. The mean transverse diameter of the aneurysm was 4.1 cm (3-7.5). Aneurysm was found in 2.3% of subjects younger than 65 years and 8.3% of subjects aged over 65 years.

CONCLUSIONS

In this sample the prevalence of abdominal aortic aneurysms was 5.9%, affecting predominantly males, with a notorious increase with advanced age.

摘要

背景

腹主动脉瘤的发病率呈上升趋势。其诱发因素包括吸烟、高血压和血脂异常。动脉瘤的逐渐增大可能导致破裂，其死亡率超过80%。

目的

评估智利有心血管危险因素的人群中腹主动脉瘤的患病率。

对象与方法

通过公开媒体发布公告，邀请年龄超过60岁、吸烟、患有高血压和/或患有闭塞性动脉疾病的个体参与一项包括病史和体格检查的研究。对所有触诊不到主动脉或怀疑有扩张的受试者进行主动脉超声检查。主动脉直径超过3 cm被视为动脉瘤。

结果

对356名年龄为67.1±6.7岁（73.9%为男性）的受试者进行了评估。研究组中62%为高血压患者，39%血脂异常，46%吸烟。已知患有冠心病或外周动脉疾病的分别占14%和10%。159名受试者需要进行超声检查。21人（5.9%）检测到动脉瘤，男性为7.6%，女性为1.1%。动脉瘤的平均横径为4.1 cm（3 - 7.5 cm）。65岁以下的受试者中动脉瘤发生率为2.3%，65岁以上的受试者中为8.3%。