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口咽重建:当前的技术水平

Oropharyngeal reconstruction: current state of the art.

作者信息

Sabri Alain

机构信息

Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA.

出版信息

Curr Opin Otolaryngol Head Neck Surg. 2003 Aug;11(4):251-4. doi: 10.1097/00020840-200308000-00006.

Abstract

Oropharyngeal reconstruction represents one of the greatest challenges in the surgical rehabilitation of patients with head and neck cancer. This article reviews several reconstruction methods, starting with the primary closure and healing by secondary intention all the way to the complex sensate microvascular flap reconstructions. Small defects such as tonsillar, small tongue base, and partial palatal defects may be closed primarily or left to granulate. This is assuming that there is no communication with the neck or bone exposure. Local flaps such as the palatal island, submental, and buccal mucosal flaps are used to close small to moderate-sized defects. Split-thickness skin grafts are also appropriate for small to moderate-sized defects. Larger defects such as total palatal, more than 50% of the tongue base, and composite tongue base/palatal/pharyngeal defects may be closed with regional myocutaneous pedicled flaps such as the pectoralis major, lower trapezius, or latissimus dorsi pedicled flaps. Microvascular tissue transfer is an excellent alternative for closure of moderate to large-sized defects. Free tissue transfer includes the radial forearm and the lateral arm free flaps. Both of these can have a sensory component. Free jejunal flaps are used for total or subtotal hypopharyngeal defects. Free gastro-omental flaps may be used for oropharyngeal and hypopharyngeal reconstruction as well. For defects involving bone, fibular flaps are an excellent option and can provide sensation. The scapular free flap may be used as well and offers the advantage of having two skin paddles (scapular and parascapular) for internal and external lining. Following a reconstructive ladder is extremely important in ensuring good function and, hence, improved quality of life.

摘要

口咽重建是头颈癌患者外科康复中最具挑战性的任务之一。本文回顾了几种重建方法,从一期缝合和二期愈合,一直到复杂的带感觉的微血管皮瓣重建。扁桃体、小舌根和部分腭部缺损等小缺损可一期缝合或任其肉芽生长。前提是与颈部无相通且无骨质暴露。局部皮瓣如腭岛瓣、颏下瓣和颊黏膜瓣用于闭合中小尺寸的缺损。中厚皮片移植也适用于中小尺寸的缺损。较大的缺损如全腭部、超过50%的舌根以及复合性舌根/腭部/咽部缺损,可用区域性带蒂肌皮瓣如胸大肌、下斜方肌或背阔肌带蒂皮瓣闭合。微血管组织移植是闭合中大型缺损的极佳选择。游离组织移植包括桡侧前臂游离皮瓣和上臂外侧游离皮瓣。这两种皮瓣都可带有感觉成分。游离空肠瓣用于下咽全缺损或次全缺损。游离胃网膜瓣也可用于口咽和下咽重建。对于涉及骨质的缺损,腓骨瓣是极佳选择且可提供感觉功能。肩胛游离皮瓣也可使用,其优点是有两个皮瓣(肩胛皮瓣和肩胛旁皮瓣)可分别用于内衬和外衬。遵循重建阶梯对于确保良好功能从而改善生活质量极为重要。

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