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1
Pectoralis Major Myocutaneous Flap Reconstruction for the Mandibular Defects in Advanced Oral Cavity Malignancies: A Retrospective Study of 30 Cases.胸大肌肌皮瓣修复晚期口腔恶性肿瘤下颌骨缺损:30例回顾性研究
Indian J Otolaryngol Head Neck Surg. 2018 Sep;70(3):415-420. doi: 10.1007/s12070-018-1429-x. Epub 2018 Jun 20.
2
Combined Use of Pectoralis Major Myocutaneous Flap and Deltopectoral Flap for the Reconstruction of Advanced Oral Cancers: Our Experience in 29 Cases.胸大肌肌皮瓣联合三角肌胸大肌皮瓣用于晚期口腔癌重建:我们的29例经验
J Maxillofac Oral Surg. 2022 Jun;21(2):312-319. doi: 10.1007/s12663-020-01464-2. Epub 2020 Oct 15.
3
Pectoralis major myocutaneous flap in head and neck reconstruction: An experience in 100 consecutive cases.胸大肌肌皮瓣在头颈部重建中的应用:100例连续病例经验
Natl J Maxillofac Surg. 2015 Jan-Jun;6(1):37-41. doi: 10.4103/0975-5950.168225.
4
Continuous validity of pedicled myocutaneous and myofascial flaps in reconstruction after surgery for head and neck cancer.带蒂肌皮瓣和肌筋膜瓣在头颈癌术后重建中的持续有效性。
J Egypt Natl Canc Inst. 2009 Sep;21(3):249-63.
5
The folded, bipaddled pectoralis major myocutaneous flap for complex oral cavity defects: Undiminished relevance in the era of free flaps.用于复杂口腔缺损的折叠双叶胸大肌肌皮瓣:在游离皮瓣时代仍具有重要意义
JPRAS Open. 2020 Nov 25;27:108-118. doi: 10.1016/j.jpra.2020.11.007. eCollection 2021 Mar.
6
PMMC Flap Revisited and its Clinical Outcome in 150 Patients.股薄肌肌皮瓣回顾及其150例患者的临床结果
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7
Reconstruction for Complex Oromandibular Facial Defects: The Fibula Free Flap and Pectoralis Major Flap Combination.复杂口腔颌面部缺损的重建:游离腓骨瓣与胸大肌瓣联合应用
Case Rep Surg. 2019 Mar 26;2019:8451213. doi: 10.1155/2019/8451213. eCollection 2019.
8
Bipaddle Pectoralis Major Myocutaneous Flap (PMMC) for Complex Composite Oral Cavity Defects: An Experience of a Tertiary Cancer Centre.双叶胸大肌肌皮瓣修复复杂口腔颌面部复合组织缺损:一家三级癌症中心的经验
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Bipaddle Pectoralis Major Myocutaneous Flap for Single Stage Reconstruction of Oromandibular Defects.双叶胸大肌肌皮瓣一期修复口腔颌面部缺损
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10
Crossed pectoralis major myocutaneous flap for recurrent oral cavity cancers.胸大肌交叉肌皮瓣用于复发性口腔癌
Ann Maxillofac Surg. 2016 Jul-Dec;6(2):219-222. doi: 10.4103/2231-0746.200320.

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Unravelling the Hidden Complication: Costal Osteomyelitis of the PMMC Donor Site.揭开隐匿的并发症:胸大肌下乳房重建供区肋骨骨髓炎
Indian J Otolaryngol Head Neck Surg. 2025 Jul;77(7):2670-2673. doi: 10.1007/s12070-025-05553-x. Epub 2025 May 21.
2
'Nasolabial Flap': A Versatile Solution for Oromandibular Defect Reconstructions in Patients with Lip and Oral Cavity Malignancies.“鼻唇瓣”:唇与口腔恶性肿瘤患者口下颌缺损重建的通用解决方案
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Can Lateral Thoracic Artery Preservation Improve Results in Large PMMC Flaps? - Our Experience of 61 Cases from Northern India.保留胸外侧动脉能否改善大型胸大肌肌皮瓣的手术效果?——我们来自印度北部的61例病例经验
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10-Year Experience with the Modified Pectoralis Major Flap: The Use of the Deltopectoral Flap to Reduce Skin Tension.改良胸大肌肌皮瓣的十年经验:使用三角胸肌皮瓣减轻皮肤张力。
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Mango-shaped Bi-paddled pectoralis major myocutaneous flap reconstruction for large full-thickness defects post resection of squamous cell carcinoma of oral cavity: An analysis of 232 cases.芒果形双叶胸大肌肌皮瓣修复口腔鳞状细胞癌切除术后大面积全层缺损:232例分析
Natl J Maxillofac Surg. 2022 May-Aug;13(2):216-222. doi: 10.4103/njms.njms_374_21. Epub 2022 Jul 15.
7
Effect of Different Repair and Reconstruction Methods Combined with Psychological Intervention on Quality of Life and Negative Emotion in Patients with Oral Cancer.不同修复重建方法联合心理干预对口腔癌患者生活质量及负性情绪的影响。
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Changing trend in the management of head neck cancers during the COVID-19 pandemic.COVID-19 大流行期间头颈部癌症治疗方式的变化趋势。
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9
Assessment of Masticatory Function in Oral Cancer Patients with Mandibulectomy Followed by Pectoralis Major Myocutaneous Flap Reconstruction.下颌骨切除术后采用胸大肌肌皮瓣重建的口腔癌患者咀嚼功能评估
Indian J Surg Oncol. 2019 Dec;10(4):620-623. doi: 10.1007/s13193-019-00955-0. Epub 2019 Aug 11.

本文引用的文献

1
[Pectoralis major flaps. Evolution of their use in the age of microvascularized flaps].[胸大肌皮瓣。在微血管皮瓣时代其应用的演变]
Acta Otorrinolaringol Esp. 2008 Jun-Jul;59(6):263-8.
2
Salvage reconstruction of extensive recurrent oral cancer defects with the pectoralis major myocutaneous flap.采用胸大肌肌皮瓣对广泛复发性口腔癌缺损进行挽救性重建。
J Oral Maxillofac Surg. 2007 Oct;65(10):1935-9. doi: 10.1016/j.joms.2006.10.067.
3
The pectoralis major flap in head and neck reconstruction: first 500 patients.胸大肌皮瓣在头颈部重建中的应用:首批500例患者
J Craniomaxillofac Surg. 2006 Sep;34(6):340-3. doi: 10.1016/j.jcms.2006.04.001. Epub 2006 Jul 24.
4
Pectoralis major and other myofascial/myocutaneous flaps in head and neck cancer reconstruction: experience with 437 cases at a single institution.胸大肌及其他肌筋膜/肌皮瓣在头颈癌重建中的应用:单机构437例经验
Head Neck. 2004 Dec;26(12):1018-23. doi: 10.1002/hed.20101.
5
Pectoralis major myocutaneous flap vs revascularized free tissue transfer: complications, gastrostomy tube dependence, and hospitalization.胸大肌肌皮瓣与血管化游离组织移植:并发症、胃造瘘管依赖及住院情况
Arch Otolaryngol Head Neck Surg. 2004 Feb;130(2):181-6. doi: 10.1001/archotol.130.2.181.
6
Oropharyngeal reconstruction: current state of the art.口咽重建:当前的技术水平
Curr Opin Otolaryngol Head Neck Surg. 2003 Aug;11(4):251-4. doi: 10.1097/00020840-200308000-00006.
7
Reconstruction of circumferential pharyngoesophageal defects with laryngotracheal flap and pectoralis major myocutaneous flap.采用喉气管瓣和胸大肌肌皮瓣修复环周性咽食管缺损。
Head Neck. 2002 Oct;24(10):933-9. doi: 10.1002/hed.10149.
8
Pectoralis major myocutaneous pedicled flap in head and neck reconstruction: retrospective review of indications and results in 244 consecutive cases at the Toronto General Hospital.胸大肌肌皮带蒂皮瓣在头颈部重建中的应用:对多伦多综合医院连续244例病例的适应证及结果的回顾性研究
J Otolaryngol. 2001 Feb;30(1):34-40. doi: 10.2310/7070.2001.21011.
9
[Free radial forearm flap and myocutaneous flaps in oncological reconstructive surgery of the oral cavity, Comparison of functional results].[游离桡侧前臂皮瓣和肌皮瓣在口腔肿瘤重建手术中的应用:功能结果比较]
Minerva Chir. 1998 Mar;53(3):183-92.
10
The deltopectoral flap v the pectoralis major myocutaneous flap. Which one?三角肌胸大肌皮瓣与胸大肌肌皮瓣。选哪一个?
Arch Otolaryngol. 1984 Jan;110(1):35-40. doi: 10.1001/archotol.1984.00800270039011.

胸大肌肌皮瓣修复晚期口腔恶性肿瘤下颌骨缺损:30例回顾性研究

Pectoralis Major Myocutaneous Flap Reconstruction for the Mandibular Defects in Advanced Oral Cavity Malignancies: A Retrospective Study of 30 Cases.

作者信息

Pradhan Pradeep, Samal Swagatika, Preetam C, Samal Dillip Kumar, Parida Pradipta Kumar

机构信息

Department of Otorhinolaryngology, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2018 Sep;70(3):415-420. doi: 10.1007/s12070-018-1429-x. Epub 2018 Jun 20.

DOI:10.1007/s12070-018-1429-x
PMID:30211100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6127056/
Abstract

To evaluate the utility of the pectoralis major myocutaneous (PMMC) flap for the reconstruction of the mandible in advanced oral cavity malignancies in the Indian population. It was a retrospective study contained 30 patients with advanced oral cancer from July 2012 to August 2016. The PMMC reconstruction was done in all the patients to repair the bony defects in segmental/hemi mandibulectomy. The patients were followed up for a mean period of 6 months in the postoperative period and the utility of the PMMC flaps were evaluated. The mean age of the patients was 45 years (range 30-63 years). The average Karnofsky performance status score was 70 and majority of the patients had history of chronic medical illness. Of the 30 PMMC flaps, partial necrosis of the skin was noticed 2 (06.66%) patients. Orocutaneous fistula was detected in 2 (06.66%) patient and 3 (10%) patients presented with wound dehiscent in the immediate postoperative period. 3 (10%) patients had recurrence of the disease. PMMC flap can be a reliable option for advanced oral malignancies, especially in patients with poor status with the coexisting chronic illness. Due to the presence of a definite vascular pedicle, ease of harvesting the flap, quick surgical procedure, and the minimal postoperative morbidities, it can be considered as a valid alternative to the free flap to repair the bony defect, especially in patients with low socioeconomic corridor like India.

摘要

评估胸大肌肌皮瓣(PMMC)在印度人群晚期口腔恶性肿瘤下颌骨重建中的应用价值。这是一项回顾性研究,纳入了2012年7月至2016年8月期间的30例晚期口腔癌患者。所有患者均采用PMMC重建术修复节段性/半侧下颌骨切除术后的骨缺损。术后对患者进行了平均6个月的随访,并评估了PMMC皮瓣的应用效果。患者的平均年龄为45岁(范围30 - 63岁)。平均卡诺夫斯基功能状态评分为70分,大多数患者有慢性病史。在30例PMMC皮瓣中,2例(06.66%)患者出现皮肤部分坏死。2例(06.66%)患者检测到口皮瘘,3例(10%)患者在术后即刻出现伤口裂开。3例(10%)患者疾病复发。PMMC皮瓣对于晚期口腔恶性肿瘤是一种可靠的选择,尤其是对于伴有慢性疾病且身体状况较差的患者。由于存在明确的血管蒂,皮瓣切取容易,手术操作迅速,术后并发症少,它可被视为修复骨缺损的游离皮瓣的有效替代方案,特别是在像印度这样社会经济水平较低的地区。