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宿主细胞膜对白色念珠菌侵入期反应的超微结构评估。

An ultrastructural evaluation of the reaction of the host cell membrane to the invasive phase of Candida albicans.

作者信息

Rajasingham K C, Challacombe S J

机构信息

Department of Oral Medicine and Pathology, United Medical School, Guy's Hospital, (University of London), Great Britain.

出版信息

Cytobios. 1992;70(281):115-22.

PMID:1451532
Abstract

Ultrastructural studies of the invasive form of Candida albicans in patients with acute or chronic candidosis have demonstrated either (a) a close seal between the host cell membrane and the fungal cell wall or (b) a ruptured or damaged host cell membrane at the point of invasion. This was observed in samples from either oral or vaginal candidosis as the pathogen successfully enters the adjoining host cell. The variations appear to be related to the degree of resistance of the host cell membrane to the invading pathogen. This view is discussed.

摘要

对患有急性或慢性念珠菌病患者体内白色念珠菌侵袭形式的超微结构研究表明,要么(a)宿主细胞膜与真菌细胞壁之间紧密封闭,要么(b)在侵袭点处宿主细胞膜破裂或受损。在口腔或阴道念珠菌病的样本中观察到了这种情况,因为病原体成功进入相邻的宿主细胞。这些差异似乎与宿主细胞膜对入侵病原体的抵抗程度有关。对此观点进行了讨论。

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