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关于骨组织骨折及骨组织愈合的建模

On the modelling bone tissue fracture and healing of the bone tissue.

作者信息

Doblaré Manuel, García José Manuel

机构信息

Group of Structures and Material Modelling, Aragón Institute of Engineering Research (I3A), University of Zaragoza, Spain.

出版信息

Acta Cient Venez. 2003;54(1):58-75.

Abstract

This paper reviews the available literature on computational modelling in two areas of bone biomechanics: fracture and healing. Bone fracture analysis attempts to predict the failure of musculoskeletal structures by several possible mechanisms under different loading conditions. However, as opposed to structurally inert materials, bone is a living tissue that can repair itself. An exciting new field of research is being developed to better comprehended these mechanisms and the mechanical behaviour of bone tissue. One of the main goals of this work is to demonstrate, after a review of computational models, the main similarities and differences between normal engineering materials and bone tissue from a structural point of view. We also underline the importance of computational simulations in biomechanics due to the difficulty of obtaining experimental or clinical results.

摘要

本文综述了骨生物力学两个领域(骨折与愈合)中有关计算建模的现有文献。骨折分析试图通过不同加载条件下的几种可能机制来预测肌肉骨骼结构的失效。然而,与结构惰性材料不同,骨是一种能够自我修复的活组织。一个令人兴奋的新研究领域正在发展,以更好地理解这些机制以及骨组织的力学行为。这项工作的主要目标之一是在回顾计算模型之后,从结构角度展示正常工程材料与骨组织之间的主要异同。我们还强调了由于获取实验或临床结果存在困难,计算模拟在生物力学中的重要性。

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