Thompson Robert L, Lavin Bruce, Talbot George H
Infectious Disease Section, Group Health Cooperative of Puget Sound, Seattle, WA 98112, USA.
South Med J. 2003 Aug;96(8):818-20. doi: 10.1097/01.SMJ.0000047962.61701.57.
A 56-year-old man with diabetes mellitus and cadaveric renal transplantation had vancomycin-resistant Enterococcus faecium tricuspid valve endocarditis. Relapse followed 6 weeks of treatment with intravenous gentamicin and high-dose ampicillin. On the basis of previous data suggesting the potential for synergistic activity of quinupristin/dalfopristin plus high-dose ampicillin, therapy with this combination was administered for 63 days. Cure was achieved and later confirmed at 2-year follow-up.
一名56岁患有糖尿病且接受尸体肾移植的男性发生了耐万古霉素屎肠球菌三尖瓣心内膜炎。在接受静脉注射庆大霉素和高剂量氨苄西林治疗6周后病情复发。基于先前数据提示奎奴普丁/达福普汀与高剂量氨苄西林可能具有协同活性，给予该联合治疗63天。患者治愈，2年随访时得到证实。
