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脊髓炎性肌纤维母细胞瘤:病例报告及文献复习

Inflammatory myofibroblastic tumour of the spinal cord: case report and review of the literature.

作者信息

Despeyroux-Ewers M, Catalaâ I, Collin L, Cognard C, Loubes-Lacroix F, Manelfe C

机构信息

Department of Diagnostic and Therapeutic Neuroradiology, Hôpital Purpan, Place du Docteur Baylac, 31059 Toulouse, France.

出版信息

Neuroradiology. 2003 Nov;45(11):812-7. doi: 10.1007/s00234-003-1069-y. Epub 2003 Sep 27.

DOI:10.1007/s00234-003-1069-y
PMID:14517703
Abstract

Inflammatory myofibroblastic tumours (IMT), also called inflammatory pseudotumours, nodular lymphoid hyperplasia, plasma-cell granuloma and fibrous xanthoma, are rare soft-tissue lesions characterised by inflammatory cells and a fibrous stroma. Clinically and radiologically, they may look like malignant tumours. They rarely affect the central nervous system and are very rare in the spinal cord. We report an IMT of the spinal cord in a 22-year-old woman presenting with spinal cord compression and a cauda equina syndrome. MRI showed a lesion at T9 with extramedullary and intramedullary components giving low signal on T2-weighted images and enhancing homogeneously. Pial lesions on the lumbar enlargement and thoracic spinal were present 11 months after surgery, when the lesion recurred. We present the radiological, operative and pathological findings and review the literature.

摘要

炎症性肌纤维母细胞瘤(IMT),也被称为炎性假瘤、结节性淋巴组织增生、浆细胞性肉芽肿和纤维性黄色瘤,是一种罕见的软组织病变,其特征为炎症细胞和纤维性基质。在临床和放射学上,它们可能看起来像恶性肿瘤。它们很少累及中枢神经系统,在脊髓中极为罕见。我们报告一例22岁女性的脊髓IMT,该患者表现为脊髓压迫和马尾综合征。磁共振成像(MRI)显示T9水平有一病变,有髓外和髓内成分,在T2加权图像上呈低信号且均匀强化。术后11个月病变复发时,在腰膨大及胸段脊髓发现软膜病变。我们展示了放射学、手术及病理学检查结果并对文献进行了回顾。

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本文引用的文献

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Spinal Cord. 2002 Apr;40(4):203-6. doi: 10.1038/sj.sc.3101271.
2
Inflammatory pseudotumor of lymph node and spleen: an entity biologically distinct from inflammatory myofibroblastic tumor.淋巴结和脾脏炎性假瘤:一种生物学上与炎性肌成纤维细胞瘤不同的实体。
Hum Pathol. 2001 Dec;32(12):1382-7. doi: 10.1053/hupa.2001.29679.
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Inflammatory pseudotumor of the maxillary sinus.
从分子诊断到当前治疗的炎性肌纤维母细胞瘤。
Oncol Res. 2024 Jun 20;32(7):1141-1162. doi: 10.32604/or.2024.050350. eCollection 2024.
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AIDS Res Ther. 2022 Dec 24;19(1):66. doi: 10.1186/s12981-022-00492-x.
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Childs Nerv Syst. 2023 Feb;39(2):331-342. doi: 10.1007/s00381-022-05789-w. Epub 2022 Dec 14.
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