McKee Vickie, Nelson Jane, Town Raewyn M
Chemistry Department, Loughborough University, UK LE11 3TU.
Chem Soc Rev. 2003 Sep;32(5):309-25. doi: 10.1039/b200672n.
The association between azacryptand hosts and oxoanion guests is reviewed. Positively charged hosts are the most effective; we focus on protonated azacryptands. Assessment of quantitative data suggests an anion cryptate effect and provides clear evidence for charge-based selectivity. Crystal structures show both cavity and cleft binding sites for anions within the series of cryptands studied. These two binding modes exhibit different pH dependence offering the possibility for design of monitoring/clean-up strategies based on a variation of appropriate host(s) and pH conditions.
本文综述了氮杂穴醚主体与含氧阴离子客体之间的关联。带正电荷的主体最为有效；我们重点关注质子化的氮杂穴醚。对定量数据的评估表明存在阴离子穴合物效应，并为基于电荷的选择性提供了明确证据。晶体结构显示了在所研究的一系列穴醚中阴离子的腔穴和裂隙结合位点。这两种结合模式表现出不同的pH依赖性，为基于合适主体和pH条件变化设计监测/净化策略提供了可能性。
