Iagubov A S, Mashkovtsev Iu V, Kulikov L S, Bogush I G
N. N. Blokhin Cancer Research Centre, 115478, Moscow.
Arkh Patol. 2003 Jul-Aug;65(4):37-40.
Electron-microscopic examination of 5 cases with histological diagnosis of Manganotti's cheilitis was made. As distinct from other types of heilitis, disintegration of the basement membrane (up to its disappearance in some areas) and pronounced changes in the basement layer of the epithelium are characteristic for this type. Shedding of plasmalemms, a decrease of desmosomal complexes, appearance of microvilli were seen in the basal cells of the epithelium. A pronounced reaction of blood and connective tissue cells which invade basal and spinous layer of the epithelium was observed.
对5例经组织学诊断为曼加诺蒂唇炎的病例进行了电子显微镜检查。与其他类型的唇炎不同,这种类型的特征是基底膜崩解(在某些区域直至消失)以及上皮基底层出现明显变化。在上皮基底细胞中可见质膜脱落、桥粒复合体减少、微绒毛出现。观察到血液和结缔组织细胞侵入上皮基底层和棘层的明显反应。