[RET原癌基因缺失与散发性C细胞癌侵袭性病程的关联]
[Association of deletions of the RET proto-oncogene wtih aggressive course of sporatic C-cell carcinoma].
作者信息
Musholt P B, Musholt T J, Moley J F, Scheumann G F
机构信息
Klinik für Abdominal- u. Transplantationschirurgie, Medizinische Hochschule Hannover.
出版信息
Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):261-5.
PMID:14518256
Abstract
A growing number of reports describing the association of certain deletions within exon 11 of the RET proto-oncogene with aggressive courses of medullary thyroid carcinoma, point to a potential prognostic relevance of molecular features in the sporadic tumor, analogous to the hereditary variant.
摘要
越来越多的报告描述了RET原癌基因第11外显子内某些缺失与甲状腺髓样癌侵袭性病程之间的关联，这表明散发性肿瘤中分子特征具有潜在的预后相关性，类似于遗传性变异。
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