Unbehaun N, Barthlen W, Kaffenberger W, Holzmann B, Bartels H, Siewert J R
Chirurgische Klinik und Poliklinik der TU München, Klinikum rechts der Isar, München.
Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):457-9.
Phagocyte functions such as respiratory burst or phagocytic activity allow the determination of septic courses. Already in case of surgical stress a reduced constitutive generation of reactive oxygen metabolites could be shown, which is assumed to influence the outcome of following septic courses. The results of septic patients suggest that in spite of a functioning uptake of particles and germs (phagocytosis) a defect of intracellular killing (respiratory burst) exists.
吞噬细胞功能,如呼吸爆发或吞噬活性,有助于确定败血症病程。在手术应激情况下,已证实活性氧代谢产物的组成性生成减少,这被认为会影响后续败血症病程的结果。败血症患者的结果表明,尽管存在对颗粒和细菌的有效摄取(吞噬作用),但仍存在细胞内杀伤缺陷(呼吸爆发)。