Gieseler R, Peters J H, Schlemminger R
Abteilung für Immunologie, Universitätskliniken Göttingen, Georg-August-Universität, D-37075 Göttingen.
Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):651-4.
It is not clear how initial therapy with CsA effects indefinite allograft acceptance after small bowel transplantation in the rat. Our study of post-transplant alterations of immune parameters within donor-type mesenteric lymph nodes suggests CsA-dependent, Th2-mediated induction of graft-specific T-cell tolerance.
尚不清楚环孢素A(CsA)的初始治疗如何影响大鼠小肠移植后同种异体移植物的长期存活。我们对供体型肠系膜淋巴结内免疫参数移植后变化的研究表明,CsA依赖、Th2介导诱导移植物特异性T细胞耐受。