Speciale John, de Lahunta Alexander
Veterinary Neurology, Fairport Animal Hospital, 117 North Main Street, Fairport, New York 14450, USA.
J Am Anim Hosp Assoc. 2003 Sep-Oct;39(5):459-62. doi: 10.5326/0390459.
A 5-year-old Staffordshire terrier exhibited slowly progressive signs of cerebellar disease, including nystagmus and dysmetria. After a 30-month course, the dog was euthanized. Grossly, the cerebellum was small and comprised only 5% of the brain weight. Histopathological examination of the brain documented diffuse degeneration. Purkinje cells were most depleted, but granular cells and the molecular layer of cerebellum were also depleted. The history and necropsy examination were evidence of late-onset primary cerebellar degeneration.
一只5岁的斯塔福郡斗牛梗表现出小脑疾病的缓慢进展症状，包括眼球震颤和辨距障碍。经过30个月的病程后，这只狗被安乐死。大体观察，小脑体积小，仅占脑重量的5%。对大脑进行组织病理学检查发现弥漫性变性。浦肯野细胞缺失最为严重，但颗粒细胞和小脑分子层也有缺失。病史和尸检结果证明这是一例迟发性原发性小脑变性。
