Alió Jorge L, Belda Jose I, Osman Amr A, Shalaby Ahmad M M
Instituto Oftalmológico de Alicante, Alicante - Miguel Hernández University, Alicante, Spain
J Refract Surg. 2003 Sep-Oct;19(5):516-27. doi: 10.3928/1081-597X-20030901-06.
To assess whether topography-driven laser in situ keratomileusis (LASIK) can correct induced corneal irregular astigmatism.
A prospective non-comparative case series of 41 eyes (38 patients) with irregular astigmatism following corneal refractive surgery, included two groups: Group 1 (26 eyes) with a defined topographic pattern and Group 2 (15 eyes) with no pattern. Ablation was performed using the Technolas 217C excimer laser with a software ablation program (TOPOLINK) based on corneal topography. Uncorrected and best spectacle-corrected visual acuity, manifest and cycloplegic refraction, corneal topography, superficial corneal surface quality, and image distortion were measured.
At 6 months follow-up in Group 1 eyes (defined topographic pattern) mean preoperative BSCVA improved from 0.16 +/- 0.11 LogMAR (0.4 to 0) to 0.09 +/- 0.10 LogMAR (0.2 to 0) (P = .001) (safety index of 1.1). In Group 2 eyes (no pattern), mean preoperative BSCVA was 0.18 +/- 0.11 LogMAR (0.4 to 0), similar to the postoperative BSCVA of 0.17 +/- 0.10 LogMAR (0.3 to 0) (safety index of 0.98). Mean postoperative UCVA was > or = 0.3 LogMAR in 25 eyes (96.2%) in Group 1 (efficacy index of 0.8) and 7 eyes (46.6%) in Group 2 (efficacy index of 0.5). Both superficial corneal surface quality and image distortion significantly improved in Group 1; there were no significant changes in Group 2. We reoperated nine eyes (21.9%).
Topographic-assisted LASIK was helpful in selected cases where irregular astigmatism showed a pattern. It was ineffective in undefined irregular astigmatism. Partial correction of the irregularity and regression of the obtained effect was common.
评估地形引导的准分子原位角膜磨镶术(LASIK)能否矫正诱导性角膜不规则散光。
一项前瞻性非对照病例系列研究,纳入41只眼(38例患者),这些患者在角膜屈光手术后出现不规则散光,分为两组:第1组(26只眼)有明确的地形图模式,第2组(15只眼)无模式。使用Technolas 217C准分子激光和基于角膜地形图的软件消融程序(TOPOLINK)进行消融。测量未矫正和最佳眼镜矫正视力、显验光和睫状肌麻痹验光、角膜地形图、角膜表面质量和图像畸变。
在第1组眼(有明确地形图模式)随访6个月时,术前平均最佳矫正视力从0.16±0.11 LogMAR(0.4至0)提高到0.09±0.10 LogMAR(0.2至0)(P = 0.001)(安全指数为1.1)。在第2组眼(无模式)中,术前平均最佳矫正视力为0.18±0.11 LogMAR(0.4至0),与术后最佳矫正视力0.17±0.10 LogMAR(0.3至0)相似(安全指数为0.98)。第1组25只眼(96.2%)术后平均裸眼视力≥0.3 LogMAR(疗效指数为0.8),第2组7只眼(46.6%)术后平均裸眼视力≥0.3 LogMAR(疗效指数为0.5)。第1组角膜表面质量和图像畸变均显著改善;第2组无显著变化。我们对9只眼(21.9%)进行了再次手术。
地形辅助LASIK在不规则散光呈现模式的特定病例中是有帮助的。在未明确的不规则散光中无效。不规则度的部分矫正和所获效果的消退很常见。