Molt O, Rübeling D, Schrader T
Philipps-Universität Marburg, Fachbereich Chemie, Hans-Meerwein-Strasse, 35032 Marburg.
J Am Chem Soc. 2003 Oct 8;125(40):12086-7. doi: 10.1021/ja035212l.
The new highly preorganized tweezer molecule 1 binds noradrenaline in polar solvents with unprecedented specificity. It uses a biomimetic recognition pattern and rejects almost all other neurotransmitters. LB experiments on a film balance reflect the same selectivity if 1 is incorporated into a stearic acid monolayer.
新型高度预组织化镊子分子1在极性溶剂中以前所未有的特异性结合去甲肾上腺素。它采用仿生识别模式,几乎排斥所有其他神经递质。如果将1掺入硬脂酸单分子层中,在膜天平上进行的LB实验也反映出相同的选择性。