Wilson Leslie, Lin Eddie, Lalwani Anil
Health Policy and Economics, University of California-San Francisco, 3333 California, Suite 420M, Box 0613, San Francisco, CA 94143, USA.
Laryngoscope. 2003 Oct;113(10):1736-45. doi: 10.1097/00005537-200310000-00015.
Despite the utility of intraoperative facial nerve monitoring in reducing the risk of iatrogenic facial nerve injury during neurotologic surgery, its routine use during primary or revision surgery remains controversial. One of the major barriers to its acceptance is cost. This study evaluates the cost-effectiveness of intraoperative facial nerve monitoring during middle ear or mastoid surgery.
RESEARCH DESIGN/METHODS: A simple decision analytic cost-effectiveness model and a societal approach were used to evaluate three cohorts of individuals who received (1) intraoperative facial nerve monitoring for both primary and revision middle ear or mastoid surgeries, or (2) facial nerve monitoring for revision surgeries only, or (3) no monitoring for any middle ear or mastoid surgeries.
Our results strongly favored the use of intraoperative facial nerve monitoring in all patients undergoing middle ear or mastoid surgery, adding about $222.73 to $528.00 US dollars to the total cost. The strategy to monitor primary and revision surgeries had the greatest effectiveness and lowest cost, with an average quality-adjusted life-year (QALY) of 45.68 at an average cost of $238 US dollars. Facial nerve monitoring in revision patients only had similar QALYs (45.67) and higher costs ($292.1). Finally, the strategy not to monitor had the lowest QALY (45.65) and highest cost ($449.8). The analysis was robust across a wide range of changes in both costs and probabilities.
Facial nerve monitoring is cost-effective, and its routine use should be adopted to reduce the risk of iatrogenic facial nerve injury during otologic surgery.
尽管术中面神经监测有助于降低耳科手术中医源性面神经损伤的风险,但其在初次手术或翻修手术中的常规应用仍存在争议。其被接受的主要障碍之一是成本。本研究评估了中耳或乳突手术中术中面神经监测的成本效益。
研究设计/方法:采用简单的决策分析成本效益模型和社会方法,对三组个体进行评估,这三组个体分别接受:(1)初次和翻修中耳或乳突手术均进行术中面神经监测;(2)仅对翻修手术进行面神经监测;(3)任何中耳或乳突手术均不进行监测。
我们的结果强烈支持在所有接受中耳或乳突手术的患者中使用术中面神经监测,这会使总成本增加约222.73美元至528.00美元。对初次和翻修手术均进行监测的策略效果最佳且成本最低,平均质量调整生命年(QALY)为45.68,平均成本为238美元。仅对翻修患者进行面神经监测具有相似的QALY(45.67)但成本更高(292.1美元)。最后,不进行监测的策略QALY最低(45.65)且成本最高(449.8美元)。在成本和概率的广泛变化范围内,该分析结果稳健。
面神经监测具有成本效益,应采用其常规应用以降低耳科手术中医源性面神经损伤的风险。