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产前脐带绕颈的自然病程。

The natural history of antenatal nuchal cords.

作者信息

Clapp James F, Stepanchak William, Hashimoto Kazumasa, Ehrenberg Hugh, Lopez Beth

机构信息

Department of Reproductive Biology, MetroHealth Medical Campus of Case Western Reserve University, Cleveland, Ohio 44109, USA.

出版信息

Am J Obstet Gynecol. 2003 Aug;189(2):488-93. doi: 10.1067/s0002-9378(03)00371-5.

Abstract

OBJECTIVE

The purpose of this study was to test the null hypotheses that nuchal cords occur with equal frequency throughout gestation, the presence of an antenatal nuchal cord is usually a random or chance event, nuchal cords do not usually persist, and nuchal cords do not usually produce evidence of acute fetal compromise before labor.

STUDY DESIGN

A prospective subject-, examiner-, and physician-blinded study design was used. The fetuses were examined serially at 24 to 26, 30 to 32, and 36 to 38 weeks' gestation and during labor and delivery. Measurements included: ultrasonic or visual detection of nuchal cords and assessment of fetal and neonatal well-being by using standard clinical techniques.

RESULTS

The incidence of nuchal cord rose with advancing gestation from 12% at 24 to 26 weeks to 37% at term. However, at each gestational age, its occurrence was a random or chance event and was not associated with clinical evidence of fetal compromise before labor.

CONCLUSION

Antenatal nuchal cords usually occur randomly with increased frequency in late gestation and appear to be a normal part of intrauterine life that is rarely associated with perinatal morbidity and mortality.

摘要

目的

本研究的目的是检验以下零假设:在整个妊娠期,脐带绕颈的发生频率相等;产前脐带绕颈通常是随机或偶然事件;脐带绕颈通常不会持续存在;脐带绕颈在分娩前通常不会产生急性胎儿窘迫的证据。

研究设计

采用前瞻性的受试者、检查者和医生盲法研究设计。在妊娠24至26周、30至32周、36至38周以及分娩期间对胎儿进行系列检查。测量内容包括:超声或目视检测脐带绕颈,并使用标准临床技术评估胎儿和新生儿的健康状况。

结果

脐带绕颈的发生率随着孕周增加而上升,从24至26周时的12%升至足月时的37%。然而,在每个孕周,其发生都是随机或偶然事件,且与分娩前胎儿窘迫的临床证据无关。

结论

产前脐带绕颈通常在妊娠晚期随机发生且频率增加,似乎是宫内生活的正常组成部分,很少与围产期发病率和死亡率相关。

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