Kumarasamy Nagalingeswaran, Solomon Suniti, Chaguturu Sreekanth K, Mahajan Anish P, Flanigan Timothy P, Balakrishnan P, Mayer Kenneth H
YRG Centre for AIDS Research and Education, Chennai, India.
AIDS. 2003 Oct 17;17(15):2267-9. doi: 10.1097/00002030-200310170-00019.
We investigated the safety, tolerability and effectiveness of locally produced generic highly active antiretroviral therapy (HAART) regimens with a chart review conducted at YRG CARE, a tertiary HIV referral centre in India. A total of 333 patients had been on Indian-manufactured generic HAART for at least 3 months. In this cohort, generic HAART was safe, well tolerated and effective at increasing CD4 T-lymphocyte counts in patients with advanced HIV, comparable to the experience with proprietary HAART.
我们在印度一家三级HIV转诊中心YRG CARE进行了一项图表审查,以调查当地生产的通用型高效抗逆转录病毒疗法(HAART)方案的安全性、耐受性和有效性。共有333名患者接受印度生产的通用型HAART治疗至少3个月。在这个队列中,通用型HAART在晚期HIV患者中是安全的,耐受性良好,并且在增加CD4 T淋巴细胞计数方面是有效的,与专利HAART的经验相当。