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印度南部针对感染艾滋病毒患者的通用抗逆转录病毒药物疗法的安全性、耐受性和有效性。

The safety, tolerability and effectiveness of generic antiretroviral drug regimens for HIV-infected patients in south India.

作者信息

Kumarasamy Nagalingeswaran, Solomon Suniti, Chaguturu Sreekanth K, Mahajan Anish P, Flanigan Timothy P, Balakrishnan P, Mayer Kenneth H

机构信息

YRG Centre for AIDS Research and Education, Chennai, India.

出版信息

AIDS. 2003 Oct 17;17(15):2267-9. doi: 10.1097/00002030-200310170-00019.

Abstract

We investigated the safety, tolerability and effectiveness of locally produced generic highly active antiretroviral therapy (HAART) regimens with a chart review conducted at YRG CARE, a tertiary HIV referral centre in India. A total of 333 patients had been on Indian-manufactured generic HAART for at least 3 months. In this cohort, generic HAART was safe, well tolerated and effective at increasing CD4 T-lymphocyte counts in patients with advanced HIV, comparable to the experience with proprietary HAART.

摘要

我们在印度一家三级HIV转诊中心YRG CARE进行了一项图表审查,以调查当地生产的通用型高效抗逆转录病毒疗法(HAART)方案的安全性、耐受性和有效性。共有333名患者接受印度生产的通用型HAART治疗至少3个月。在这个队列中,通用型HAART在晚期HIV患者中是安全的,耐受性良好,并且在增加CD4 T淋巴细胞计数方面是有效的,与专利HAART的经验相当。

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